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Lipophilic Chemicals, Diabetes and Obesity

This is just a little continuation of the post made yesterday in which I wondered if associations between intake of animal protein (vs. vegetable protein) and waist circumference had anything to do with increased exposure of consumers of animal products to environmental contaminants. This is not my area of research . . . but it is an area of research for a lot of other people. Diabetes and/or Insulin Resistance is associated with exposure to Brominated Flame Retardants, Persistent Organic Pollutants, polychlorinated diphenyl ethers, and, interestingly (perhaps because I don’t understand the mechanism by which this would occur . . . will have to look into it) airborn particulates. A brief and very readable review of environmental (chemical) causes of diabetes was made in 2008 by Oliver et al.

Jones, O., Maguire, M., & Griffin, J. (2008). Environmental pollution and diabetes: a neglected association The Lancet, 371 (9609), 287-288 DOI: 10.1016/S0140-6736(08)60147-6
Lee, D., Lee, I., Jin, S., Steffes, M., & Jacobs, D. (2007). Association Between Serum Concentrations of Persistent Organic Pollutants and Insulin Resistance Among Nondiabetic Adults: Results from the National Health and Nutrition Examination Survey 1999-2002 Diabetes Care, 30 (3), 622-628 DOI: 10.2337/dc06-2190
Lim, J., Lee, D., & Jacobs, D. (2008). Association of Brominated Flame Retardants With Diabetes and Metabolic Syndrome in the U.S. Population, 2003-2004 Diabetes Care, 31 (9), 1802-1807 DOI: 10.2337/dc08-0850
Pearson JF, Bachireddy C, Shyamprasad S, Goldfine AB, & Brownstein JS (2010). Association between fine particulate matter and diabetes prevalence in the U.S. Diabetes care, 33 (10), 2196-201 PMID: 20628090

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