Activitystat is a setpoint for a person’s general activity level.
Have you ever wondered why some people are very active while others prefer to conserve their energy? People tend to keep preferred levels of activity, almost as part of their personalities. Those who are highly active may prefer lots of sports or just lots of fidgeting. They get antsy when confined. Others relax whenever possible. The ActivityStat is a term for a person’s general level of activity. “The ActivityStat hypothesis” suggests that when physical activity is increased or decreased in one domain, there will be a compensatory change in another domain, in order to maintain an overall stable level of physical activity or energy expenditure over time.” The ActivityStat leads people to maintain a certain level of activity. A person whose ActivityStat is high would probably fidget more or get up 20 times to get coffee when confined. Person whose ActivityStat is low might reduce activity for the rest of the day after a workout or play session. What determines a person’s activitystat is unknown. It might be genetic. But it may also be influenced by the environment.
The obesity epidemic is disturbing and fascinating as well. And while many have been quick to blame parents, the internet, schools and “moral failings,” there is growing evidence that unseen and poorly understood factors are involved, at least in part. These factors include current or early exposure to chemicals that have entered the environment or otherwise found their way to our food and water supplies. BPA, found in some plastics, has been a hot-button chemical. It was one of the first identified as an “endocrine disruptor” (a chemical that interacts with hormones or their receptors). While there has been a ton of research on BPA, new things keep turning up: male rats exposed to BPA very early in life, don’t move around as much as unexposed rats.
Can BPA make you gain weight? BPA also increases fat cells.
While BPA may decrease your activity stat, it also increases fat cells. At least in vitro (this is cells in a dish, rather than in a living animal). When a person is exposed to BPA, the body gets rid of it pretty quickly. It converts it to something called BPA-G. Until recently it was thought the BPA-G was harmless and could be urinated away. BPA-G added to a cell culture of potential fat cells caused the not-yet-fat cells to turn into fat cells. It also caused them to start making more fat. There may be no need to fear the occasional drink from a plastic water bottle. But people should probably stay away when possible. Especially pregnant women. Even if it says BPA-free on the label. We are just learning about BPA-free plastics, and it looks like they are much like BPA. A last word . . . these studies were of cells (or rats) eposed to BPA or BPA-G early on. The same effect may not be seen in adults. Or even humans for that matter. My apologies if this is too technical or not technical enough. For you geeks, links to the original articles are below.
NOTE: This is a disclaimer. I am not a medical doctor, I am a scientist. If you have questions about your health, talk to your medical doctor
Boucher JG, Boudreau A, Ahmed S, Atlas E. In Vitro Effects of Bisphenol A β-D-Glucuronide (BPA-G) on Adipogenesis in Human and Murine Preadipocytes.Environmental Health Perspectives. 2015;123(12):1287-1293. doi:10.1289/ehp.1409143.
Volberg V, Harley K, Calafat AM, et al. Maternal bisphenol A exposure during pregnancy and its association with adipokines in Mexican-American children.Environmental and molecular mutagenesis. 2013;54(8):621-628. doi:10.1002/em.21803.